Marical - Solutions for Global Aquaculture
Science behind MariCal
Calcium Ion Receptors
The MariCal scientific platform is built on a unique patented class of proteins called extracellular calcium ion receptor proteins (CaSRs) that allow cells to sense and respond to various concentrations of ions (e.g. calcium, magnesium and sodium) and nutrients (amino acids). CaSR-based human medical technology and pharmaceutical development is a US$1 billion international effort involving both large and small pharmaceutical companies. However, the biological roles of CaSR proteins in aquatic organisms are even greater than in humans.

MariCal uses state-of-the-art cell and molecular biology methods strictly as research tools to study the most fundamental aspects of CaSRs. None of MariCal's technology solutions for global aquaculture involve the use of molecular biology (especially GMOs), drugs or hormones as production tools.

Highlights

  • CaSRs are minute biological switches located in cell membranes
  • CaSRs sense and respond to ions and amino acids
  • CaSRs present in many organs actually coordinate the body's various responses to ions and nutrients both inside and outside the body
  • Much is known about the role of CaSRs in humans; our co-founders are involved in much of this work
  • Co-founder involvement, plus our cross-licensing agreement with a leading human pharmaceutical company, give MariCal unique knowledge of the many functions of the CaSR
  • CaSRs are the biological salinity and nutrient sensors that function as master switches for osmoregulation and growth in fish
  • CaSRs control the deposition of calcium into the shells of mollusks (oysters, clams and pearls) as well as crustaceans (shrimp, crabs and lobsters) - a process called biomineralization



CaR Chart
MariCal
207-773-2500   -  Info@MariCal.biz   -   ©  Copyright 2002-2003 MariCal
www.cienciamar.biz www.marical.no