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There is an interesting history surrounding the discovery
and development of MariCal's calcium receptor science.
Two of the company's three co-founders, Drs. Brown and
Hebert, were the first to use state-of-the-art biotechnology
techniques to characterize CaSRs in humans. These initial
discovery activities took place at Brigham and Women's
Hospital and at Harvard Medical School in Boston, Massachusetts
USA. Drs. Brown and Hebert, along with co-founder and
CEO Dr. Harris - are internationally recognized experts and
leaders in the scientific fields of the body's metabolism of
monovalent ions (i.e. sodium, Na+: SC Hebert), divalent
ions (i.e. calcium, Ca2+, magnesium, Mg2+: EM Brown)
and water (HW Harris).
Each scientist has contributed his unique and extensive
knowledge within his respective field to provide MariCal
with an unparalleled focus on fundamental aspects of CaSR
function. This team approach has not only permitted rapid
rates of scientific discovery but also produced unique
scientific insights into the structure and multiple functions
of CaSRs in aquatic organisms. Our direct connection to this
large body of expertise and research about the role and
functioning of CaSRs in mammals continues to be a huge
advantage for MariCal's focus on aquatic species.
MariCal's breakthrough research has demonstrated that
CaSRs are key 'thermostats' or switches by which fish and
other aquatic organisms sense and respond to nutrients
and salinity/ionic composition in aquatic environments.
The Company's discoveries and applications benefit from an extensive
array of legal protections with an international scope.
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 For a more extended discussion of the science behind Calcium Receptors, their role in humans, and how they function in aquatic organisms, CLICK HERE for a PDF document (You must have Adobe Acrobat Reader™ to view this document).
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